BioLINK 2009


Image Analysis Session

Session Chair: Robert Murphy, Carnegie Mellon University

Introductory Talk: Principles of Bioimage Informatics

Robert F. Murphy
Ray and Stephanie Lane Professor of Computational Biology, Carnegie Mellon University

Abstract
    High throughput microscopy is well-established for cell-based drug screening and will play
    a growing role in systems biology efforts.
    This introductory talk will describe methods for automated analysis of patterns in
    fluorescence microscope images, applicable to all types of traditional and high throughput microscopy.
    Topics covered will include:

• methods for automated segmentation of multi-cell images into single cell regions
• types of features used to describe cellular and subcellular patterns
• methods for analyzing cell, nuclear and organelle shape
• methods for building generative models to describe shapes and patterns